Rivaroxaban amine (free base)

Picture of Rivaroxaban amine (free base)

Rivaroxaban amine (free base)

4-[4-[(5S)-5-(Aminomethyl)-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone

446292-10-0

Commercialized

Sample Available

Product Details

(S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one (CAS 446292-10-0) is a chiral oxazolidinone-morpholinone amine of the (S)-aminomethyl oxazolidinone chemical class. This compound is an advanced synthetic intermediate and a key precursor in the synthesis of Rivaroxaban. It has both the important chiral oxazolidinone ring (with the (S)-configuration at C-5) and the morpholin-3-one pharmacophore in one piece. The (R)-enantiomer is the main stereoisomeric impurity.

ApiSyn offers (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one (CAS 446292-10-0) as a pharmaceutical-grade chiral intermediate and steroisomeric reference standard for Rivaroxaban process development.

Chemical Name 4-[4-[(5S)-5-(Aminomethyl)-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone
Molecular Formula C14H17N3O4
Molecular Weight 291.3
CAS Number 446292-10-0