Ganirelix Acetate is a synthetic decapeptide
gonadotropin-releasing hormone (GnRH) antagonist. Also known as Orgalutran,
Antagon. As a GnRH antagonist it acts directly at the receptor, giving rapid
suppression without the initial flare seen with GnRH agonists, which supports
shorter stimulation protocols. ApiSyn produces it by solid-phase peptide
synthesis (SPPS) in Ahmedabad, India, controlling the process from protected
amino acids through purification and salt formation. Related impurity reference
standards can be arranged through SynZeal.
| Chemical Name | (S)-1-(N2-N2-((R)-2-((R)-2-((R)-2-Acetamido-3-(naphthalen-2-yl)propanamido)-3-(4-chlorophenyl)propanamido)-3-(pyridin-3-yl)propanoyl)-L-seryl-L-tyrosyl-N6-(bis(ethylamino)methylene)-D-lysyl-L-leucyl-N6-(bis(ethylamino)methylene)-L-lysyl)-N-((R)-1-amino-1-oxopropan-2-yl)pyrrolidine-2-carboxamide acetate |
| Molecular Formula | C80H113ClN18O13 : C2H4O2 |
| Molecular Weight | 1570.3 : 60.1 |
| CAS Number | 129311-55-3 |