Product Details

Fmoc-Lys-OH Hydrochloride (CAS 139262-23-0), also known as Nα-Fmoc-L-lysine hydrochloride (free ε-amino group, HCl salt), is a rare lysine building block with only α-amino Fmoc protection and an unprotected ε-amino group (as HCl salt). It belongs to the Fmoc-lysine free epsilon-amino HCl class. This compound has the ε-amino free (as hydrochloride), unlike standard Fmoc-Lys(Boc)-OH, which has the ε-NH2 protected by Boc. Applications encompass the synthesis of branching peptides, dendrimeric peptides, or selective ε-acylation in the preparation of lipopeptides or antibody-drug conjugates. 

ApiSyn sells Fmoc-Lys-OH HCl (CAS 139262-23-0), which is a pharmaceutical-grade specialty amino acid building block and reference standard for selective lysine functionalization chemistry.