Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH

Picture of Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH

Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH

(23S,50S)-50-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-23-(tert-butoxycarbonyl)-2,2-dimethyl-4,21,26,35,44-pentaoxo-3,30,33,39,42-pentaoxa-22,27,36,45-tetraazahenpentacontan-51-oic acid

1662688-20-1

Commercialized

Sample Available

Product Details

Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH 1662688-20-1 Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH (CAS 1662688-20-1) is a complex Fmoc-lysine side chain building block bearing an octanedioic acid (C8 dicarboxylate, tBu-protected) — glutamic acid (OtBu-protected) — bis-AEEA linker, belonging to the fatty diacid-aminoethyloxy-Fmoc-Lys side chain class. This compound is an advanced SPPS building block for making Semaglutide (CAS 910463-68-2) or GLP-1 analogues that are very similar to it using a C8-based partial linker strategy. Some important impurities are incomplete deprotection products, des-AEEA truncations, and variants with mismatched fatty acid chains. 


ApiSyn sells Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH (CAS 1662688-20-1) as a pharmaceutical-grade SPPS building block for making and testing GLP-1 peptides.

Chemical Name (23S,50S)-50-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-23-(tert-butoxycarbonyl)-2,2-dimethyl-4,21,26,35,44-pentaoxo-3,30,33,39,42-pentaoxa-22,27,36,45-tetraazahenpentacontan-51-oic acid
Molecular Formula C64H101N5O16
Molecular Weight 1196.5
CAS Number 1662688-20-1