Product Details

8-Aza-5-azoniaspiro[4.5]decane, 8-(2-pyrimidinyl)-, bromide (1:1) 81461-73-6 is a quaternary ammonium spiro compound of the azaspirodecanyl-pyrimidinyl bromide chemical class. It is also known as 1-(2-pyrimidinyl)piperazinium spiro-bromide or Buspirone spiro-intermediate. This compound is a synthetic precursor and structural analogue in the synthesis of Buspirone, a non-benzodiazepine anxiolytic that acts on 5-HT1A and D2 receptors. For downstream API synthesis, ICH Q3A residual intermediate qualification is in effect. 

ApiSyn provides 8-Aza-5-azoniaspiro[4.5]decane, 8-(2-pyrimidinyl)-, bromide (CAS 81461-73-6) as a certified pharmaceutical synthetic intermediate and impurity reference standard for Buspirone-class anxiolytic API process development.