Product Details

6-Chloro-3-methyluracil (CAS 4318-56-3) is a halogenated pyrimidinedione heterocycle that belongs to the methyluracil chemical class. It is an important synthetic intermediate in the pharmaceutical industry. It is also called 6-chloro-1-methylpyrimidine-2,4(1H,3H)-dione. This compound is a key building block for making DPP-4 inhibitors like Alogliptin. Residual 6-Chloro-3-methyluracil can show up as a carryover impurity in Alogliptin API if the reaction and purification aren't done correctly. This condition means that it needs to be qualified according to ICH Q3A guidelines. 

ApiSyn offers 6-Chloro-3-methyluracil as a high-purity pharmaceutical synthetic intermediate and reference standard for developing processes and finding impurities in the synthesis of DPP-4 inhibitor APIs.