6-Chloro-3-(1-methylethyl)-2,4(1H,3H)-pyrimidinedione (CAS 887581-47-7), also known as 6-chloro-3-isopropyluracil, is a halogenated N-substituted uracil of the chloro-isopropyluracil pyrimidinedione chemical class. This substance is an important advanced intermediate in the making of Alogliptin Benzoate, a DPP-4 inhibitor for type 2 diabetes. ICH M7 assessment is necessary for Alogliptin API because it has residual amounts that need ICH Q3A qualification.
ApiSyn sells 6-Chloro-3-isopropyl-2,4(1H,3H)-pyrimidinedione (CAS 887581-47-7) as a pharmaceutical-grade intermediate and reference standard for the development of DPP-4 inhibitor APIs.
| Chemical Name | 6-Chloro-3-isopropylpyrimidine-2,4(1H,3H)-dione |
| Molecular Formula | C7H9ClN2O2 |
| Molecular Weight | 188.6 |
| CAS Number | 887581-47-7 |