Product Details

5-Bromo-4-(4-chlorothiophen-2-yl)thiazol-2-amine (CAS 2161380-87-4) is a halogenated bis-heterocyclic primary amine of the bromo-thiazolamine-chlorothienyl chemical class. This compound is an advanced synthetic intermediate used to make Mavacamten, the first cardiac myosin inhibitor for hypertrophic cardiomyopathy (HCM). Because this intermediate has both bromo and chloro electrophilic properties, it needs to be handled carefully and monitored closely during drug production. 

ApiSyn supplies 5-Bromo-4-(4-chlorothiophen-2-yl)thiazol-2-amine (CAS 2161380-87-4) as a pharmaceutical-grade synthetic intermediate and reference standard for Mavacamten process development and impurity profiling.