Seladelpar thiol intermediate

Picture of Seladelpar thiol intermediate

Seladelpar thiol intermediate

Ethyl 2-(4-mercapto-2-methylphenoxy)acetate

343322-82-7

Under Development

Product Details

Seladelpar thiol intermediate 343322-82-7 (4-Mercapto-2-methylphenoxy)acetic acid ethyl ester (CAS 343322-82-7) is a thiophenol-acetic acid ester of the mercaptomethylphenoxyacetate chemical class. This sulfur-containing intermediate is an important part of making macitentan, which is a dual endothelin receptor antagonist for pulmonary arterial hypertension (PAH).


ApiSyn supplies (4-Mercapto-2-methylphenoxy)acetic acid ethyl ester (CAS 343322-82-7) as a pharmaceutical synthetic intermediate and impurity reference standard for the development of the Macitentan API process.

Chemical Name Ethyl 2-(4-mercapto-2-methylphenoxy)acetate
Molecular Formula C11H14O3S
Molecular Weight 226.3
CAS Number 343322-82-7