(3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate (CAS 149809-43-8) is an enantiopure chiral triazolyl-difluorophenyl-tetrahydrofuranyl tosylate. It is part of the chiral antifungal triazole tetrahydrofuran tosylate chemical class. This compound is a very important late-stage synthetic intermediate in the making of Posaconazole. It gives the whole chiral THF-triazole core framework the (3S,5R) absolute configuration that is needed for antifungal activity.
This advanced Posaconazole chiral intermediate (CAS 149809-43-8) from ApiSyn is a pharmaceutical reference standard for quality control that is specific to stereospecificity.
| Chemical Name | ((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate |
| Molecular Formula | C21H21F2N3O4S |
| Molecular Weight | 449.5 |
| CAS Number | 149809-43-8 |