Product Details

3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalene-2-carbaldehyde (CAS 17610-20-7) is a polyprenyl-derived aromatic aldehyde of the tetramethyltetrahydronaphthalene-carbaldehyde (aromatic retinoid aldehyde) chemical class. This compound is an essential synthetic precursor in the production of retinoid-based pharmaceuticals. Most importantly, it is a key step in making Palovarotene, a selective RARγ agonist for fibrodysplasia ossificans progressiva (FOP), as well as other synthetic Retinoids like Bexarotene. 

ApiSyn offers this retinoid synthesis building block (CAS 17610-20-7) as a pharmaceutical intermediate and reference standard for the development of Palovarotene and Retinoid APIs.