Product Details

1-(3,4-Dimethoxyphenethyl)urea (CAS 25017-47-4) is a substituted arylethyl urea from the dimethoxyphenethylurea chemical class. This substance is an important starting point or early intermediate in the making of isoquinoline-based drugs that work on the heart and brain. The 3,4-dimethoxyphenethyl group, which is found in dopaminergic pharmacophores and is similar to the structures of papaverine, trimetazidine, and other cardiovascular drugs, is added by making urea with homoveratrylamine. The 3,4-dimethoxyphenethyl scaffold is a pharmaceutical building block that gives lipophilicity, which is important for binding to CNS or cardiovascular targets. If found as a carryover impurity in downstream APIs, ICH Q3A applies. 

ApiSyn sells 1-(3,4-Dimethoxyphenethyl)urea (CAS 25017-47-4) as a pharmaceutical-grade synthetic intermediate for process development and impurity characterization in the synthesis of isoquinoline-based APIs.